projects

My research investigates how genetic, environmental, and social determinants of health interact to shape Alzheimer’s disease risk and progression.

work

Integrated genetic-exposome risk assessment for precision dementia care

Integrating inherited susceptibility with modifiable risk burden to support earlier, more personalized dementia prevention

APOE across ancestry and environmental contexts

Defining how APOE-associated risk varies across ancestry, life stage, biomarkers, and modifiable health factors

Polygenic risk and genomic prediction of Alzheimer’s disease

Developing ancestry-aware genomic prediction across cognition, biomarkers, pathology, and clinical outcomes

Modifiable risk factors and polyexposure scores for dementia

Evaluating accessible risk scores and causal evidence for dementia-prevention targets

Mitochondrial genomics and dysfunction in cognitive aging and neurodegeneration

Studying how mitochondrial and nuclear genomic variation contributes to cognitive aging and neurodegenerative disease

COVID-19 host genetics and post-infection outcomes

Using collaborative human genetics to study susceptibility, severity, and long-term outcomes of COVID-19